Research Library

A reference list of published studies relating to the compounds in our catalogue. Entries link to the publisher or PubMed record. Listing a study does not imply any claim about the materials we supply.

  • Retatrutide (GLP3 RT)2024

    Effect of Retatrutide on Hepatic Steatosis in Adults with Obesity (Phase 2 sub-study)

    Nature Medicine

    MRI-PDFF sub-analysis reporting reductions in liver fat content in participants with metabolic dysfunction-associated steatotic liver disease.

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  • Retatrutide (GLP3 RT)2023

    Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial

    New England Journal of Medicine

    Phase 2 dose-ranging study of the GIP/GLP-1/glucagon receptor triagonist, reporting mean body-weight change at 48 weeks across dose cohorts.

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  • Retatrutide (GLP3 RT)2023

    Retatrutide in Type 2 Diabetes: A Randomised, Double-Blind Phase 2 Trial

    The Lancet

    Evaluated glycaemic endpoints (HbA1c) and weight change versus dulaglutide and placebo over 36 weeks.

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  • GLOW / KLOW (blends)2022

    Combination Peptide Formulations in Regenerative Research: A Methodological Note

    Peptide Science (review)

    Discussion of confounders when evaluating multi-peptide blends (BPC-157, TB-500, GHK-Cu, KPV) versus single-agent controls.

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  • MOTS-c2021

    MOTS-c Is an Exercise-Induced Mitochondrial-Encoded Regulator of Physical Capacity

    Nature Communications

    Reported improved exercise capacity and healthspan markers in aged mice following MOTS-c administration.

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  • NAD+2021

    NAD+ Metabolism and Its Roles in Cellular Processes During Ageing

    Nature Reviews Molecular Cell Biology

    Comprehensive review of NAD+ biosynthesis, decline with age, and consequences for sirtuin and PARP activity.

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  • Tesamorelin2019

    Tesamorelin, Liver Fat and Fibrosis in HIV: A Randomised Trial

    The Lancet HIV

    Twelve-month randomised study reporting reduced hepatic fat fraction and slowed fibrosis progression.

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  • NAD+2018

    Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence

    Cell Metabolism

    Synthesis of preclinical and early clinical evidence for precursor-based NAD+ repletion strategies.

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  • GHK-Cu2017

    Resetting Skin Genome Back to Health: GHK-Induced Gene Expression Profiling

    Cosmetics / Oncotarget

    Transcriptomic analysis reporting broad shifts in fibroblast gene expression following GHK exposure.

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  • BPC-1572016

    BPC 157 and the Gut–Brain Axis: Cytoprotection Beyond the Gastrointestinal Tract

    Current Neuropharmacology

    Overview of cytoprotective mechanisms reported across gastrointestinal, vascular and central nervous system models.

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  • Semax2016

    Neuroprotective Effects of Semax in Experimental Cerebral Ischaemia

    Journal of Molecular Neuroscience

    Transcriptome analysis of ischaemic rat brain tissue describing modulation of inflammatory and vascular gene sets.

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  • Selank2016

    Anxiolytic Activity of Selank, a Tuftsin Analogue, and Its Effect on GABAergic Genes

    Frontiers in Pharmacology / Peptides

    Preclinical characterisation of anxiolytic-like behaviour and changes in GABA-A receptor subunit expression.

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  • AOD-96042015

    AOD-9604 and Chondroprotection in Preclinical Osteoarthritis Models

    Biologics: Targets and Therapy

    Preclinical evaluation of intra-articular administration on cartilage matrix markers in animal models.

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  • MOTS-c2015

    The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis

    Cell Metabolism

    Identified MOTS-c as a regulator of the folate cycle and AMPK activation, with effects on insulin sensitivity in mice.

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  • GHK-Cu2015

    GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration

    BioMed Research International

    Review of copper-peptide effects on collagen synthesis, antioxidant enzymes and gene expression in dermal fibroblasts.

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  • Glutathione2013

    Glutathione: Antioxidant Defence, Redox Signalling and Disease

    Biochimica et Biophysica Acta

    Reference review of GSH/GSSG redox couple regulation and its role in cellular detoxification pathways.

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  • Semax2013

    Semax, an ACTH(4-10) Analogue, Modulates BDNF Expression in Rat Hippocampus

    Neuroscience Letters

    Reported upregulation of BDNF and TrkB transcripts following administration in rodent models.

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  • Wolverine Stack2012

    TB-500 / Thymosin Beta-4 in Tissue Repair and Angiogenesis

    Annals of the New York Academy of Sciences

    Review of actin-sequestering peptide activity in cardiac, dermal and corneal repair models, relevant to blended repair formulations.

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  • BPC-1572011

    Stable Gastric Pentadecapeptide BPC 157: Angiogenesis and Tendon Healing

    Journal of Orthopaedic Research / Current Pharmaceutical Design

    Review and rodent data describing accelerated tendon-to-bone healing and VEGF-mediated angiogenic signalling.

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  • KPV2008

    The Tripeptide KPV Inhibits Inflammation in Intestinal Epithelial Models

    Gastroenterology / Journal of Immunology

    Described PepT1-mediated uptake and NF-κB pathway inhibition in colitis models.

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  • Tesamorelin2007

    Effects of Tesamorelin on Visceral Adipose Tissue in HIV-Associated Lipodystrophy

    New England Journal of Medicine

    Pivotal trial of the GHRH analogue showing selective reduction of visceral adipose tissue with preserved subcutaneous fat.

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  • CJC-1295 + Ipamorelin2006

    Sustained GH and IGF-1 Elevation After Single Doses of CJC-1295 in Healthy Adults

    Journal of Clinical Endocrinology & Metabolism

    Pharmacokinetic study of the long-acting GHRH analogue reporting dose-dependent GH pulse amplification.

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  • AOD-96042004

    The Effect of the Lipolytic hGH Fragment AOD-9604 on Weight in Obese Subjects

    Obesity Research / Diabetes, Obesity and Metabolism

    Early clinical work on the hGH 177-191 fragment describing lipolytic activity without effects on IGF-1 or glucose tolerance.

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  • CJC-1295 + Ipamorelin1998

    Ipamorelin, the First Selective Growth Hormone Secretagogue

    European Journal of Endocrinology

    Characterisation of a pentapeptide GH secretagogue with minimal effect on ACTH and cortisol release.

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